Acute Pain
Volume 9, Issue 4 , Pages 193-199 , December 2007

Epidural methadone for acute post-thoracotomy pain: An alternative to a ropivacaine plus fentanyl-based patient-controlled epidural regimen

  • Jordi Perez

      Affiliations

    • Department of Anaesthesia, Hospital Clinic, University of Barcelona, Villarroel 170, Barcelona 08036, Spain
    • Corresponding Author InformationCorresponding author. Tel.: +34 93 227 5558; fax: +34 93 451 75 53.
    • ,
  • Maria-Jose Jiménez

      Affiliations

    • Department of Anaesthesia, Hospital Clinic, University of Barcelona, Villarroel 170, Barcelona 08036, Spain
    • ,
  • Gillermina Fita

      Affiliations

    • Department of Anaesthesia, Hospital Clinic, University of Barcelona, Villarroel 170, Barcelona 08036, Spain
    • ,
  • Irene Rovira

      Affiliations

    • Department of Anaesthesia, Hospital Clinic, University of Barcelona, Villarroel 170, Barcelona 08036, Spain
    • ,
  • Miquel Catalan

      Affiliations

    • Department of Thoracic Surgery, Hospital Clinic, University of Barcelona, Spain
    • ,
  • Carmen Gomar

      Affiliations

    • Department of Anaesthesia, Hospital Clinic, University of Barcelona, Villarroel 170, Barcelona 08036, Spain

Received 6 May 2007 ,Revised 24 July 2007 ,Accepted 16 August 2007.

References 

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  4. Ballantyne JC, Carr DB, DeFerranti S, Suarez T, Lau J, Chalmers TC, et al. The comparative effects of postoperative analgesic therapies on pulmonary outcome: cumulative meta-analyses of randomized, controlled trials. Anesth Analg. 1998;86:598–612
  5. Della Rocca G, Coccia C, Pompei L, Costa MG, Pierconti F, Di Marco P, et al. Post-thoracotomy analgesia: epidural vs intravenous morphine continuous infusion. Minerva Anestesiol. 2002;68:681–693
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  9. Parramon F, García Ch , Gambús P, Vilaplana J, Aragonés N, Villalonga A. Epidural methadone is more effective than intravenous methadone in postoperative patient-controlled analgesia after thoracic surgery (Article in Spanish). Rev Esp Anestesiol. 2003;50:326–331
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  17. Jeon Y, Hwang J, Kang J, Han S, Rhee K, Oh Y. Effects of epidural naloxone on pruritus induced by epidural morphine: a randomized controlled trial. Int J Obst Anesth. 2005;14:22–25
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  20. Gedney JA, Liu EH. Side-effects of epidural infusions of opioid bupivacaine mixtures. Anaesthesia. 1998;53:1148–1155
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  22. Matot I, Drenger B, Weissman C, Shauli A, Gozal Y. Epidural clonidine, bupivacaine and methadone as the sole analgesic agent after thoracotomy for lung resection. Anaesthesia. 2004;59:861–866
  23. Ginosar Y, Riley ET, Angt MS. The site of action of epidural fentanyl in humans: the difference between infusion and bolus administration. Anesth Analg. 2003;97:1428–1438

PII: S1366-0071(07)00150-7

doi: 10.1016/j.acpain.2007.08.024

Acute Pain
Volume 9, Issue 4 , Pages 193-199 , December 2007

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