Acute Pain
Volume 7, Issue 1 , Pages 33-35 , May 2005

Prospective randomised controlled trial comparing rectal versus oral paracetamol and diclofenac in children following appendicectomy

  • S.E. Willey

      Affiliations

    • University of Southampton Medical School, 12 Gravel Lane, Charlton Marshall, Blandford, Dorset DT11 9NS, UK
    • Corresponding Author InformationCorresponding author at: ENT Department, Dorset County Hospital, Williams Avenue, Dorchester, Dorset DT1 2JY, UK. Tel.: 44 1305 251150; fax: +44 1252 544 754.
  • ,
  • D.M. Griffiths

      Affiliations

    • Southampton University Hospitals Trust, Southampton, UK
  • ,
  • J.J. Nightingale

      Affiliations

    • Portsmouth Hospitals Trust, Portsmouth, UK

Received 7 August 2003 ,Revised 28 February 2005 ,Accepted 4 April 2005.

References 

  1. Morton NS. Prevention and control of pain in children. Br J Anaesth. 1999;83:118–129
  2. Coulthard KP, Neilson HW, Schroder M, Covino A, Matthews NT, Murray RS, et al. Bioavailablity and plasma paracetamol profiles of panadol suppositories in children post-operatively. J Paediatr Child Health. 1998;34(5):425–431
  3. Blume H, Ali SL, Elze M, Kramer J, Scholz ME. Relative bioavailability studies on paracetamol in suppositories as compared to tablets. Drug Res. 1996;46(10):975–980
  4. Ramakrishna S, Fadnavis NW, Diwan PV. Comparative pharmacokinetic evaluation of compressed suppositories of diclofenac sodium in humans. Arzneimittel-Forschung. 1996;46(2):175–177
  5. Morton NS. Pain assessment in children. Paediatr Anaesth. 1997;7:267–272
  6. Carter B. Child and infant pain – principles of nursing care and management. Chapman and Hall; 1994;p. 42

PII: S1366-0071(05)00010-0

doi: 10.1016/j.acpain.2005.04.001

Acute Pain
Volume 7, Issue 1 , Pages 33-35 , May 2005