Acute Pain
Volume 7, Issue 1 , Pages 37-40 , May 2005

Effects of succinylcholine on spinal antinociception with lidocaine in rats

  • Weian Zeng

      Affiliations

    • Department of Anesthesiology, Tumor Hospital, Cancer Center, Sun Yat-sen University, 651 Dong Feng Road East, Guangzhou City, Guangzhou 510060, China
    • Corresponding Author InformationCorresponding author. Tel.: +86 20 87343060; fax: +86 20 87343392.
    • ,
  • Haichun Ma

      Affiliations

    • Department of Anesthesiology, The First Hospital of Jilin University, Changchun, China
    • ,
  • Hongying Tan

      Affiliations

    • Department of Anesthesiology, Tumor Hospital, Cancer Center, Sun Yat-sen University, Guangzhou, China
    • ,
  • Shuji Dohi

      Affiliations

    • Department of Anesthesiology and Critical Care Medicine, Gifu University School of Medicine, Gifu City, Japan

Received 22 March 2004 ,Revised 5 January 2005 ,Accepted 17 January 2005.

References 

  1. Naguib M, Yaksh TL. Antinociceptive effects of spinal cholinesterase inhibition and isobolographic analysis of the interaction with m and a2 receptor systems. Anesthesiology. 1994;80:1338–1348
  2. Nedoma J, Dorofeeva NA, Tucek S, Shelkovnikov SA, Danilov AF. Interaction of the neuromuscular blocking drugs alcuronium, decamethonium, gallamine, pancuronium, ritebronium, tercuronium and d-tubocurarine with muscarinic acetylcholine receptors in the heart and ileum. Naunyn-Schmiedebergs Arch Pharmacol. 1985;329:176–181
  3. Adam LP, Henderson EG. Augmentation of succinylcholine-induced neuromuscular blockade by calcium channel antagonists. Neurosci Lett. 1986;70:148–153
  4. Kimura I, Okazaki M, Uwano T, Kobayahi S, Kimura M. Succinylcholine-induced acceleration and suppression of electrically evoked acetylcholine release from mouse phrenic nerve-hemidiaphragm muscle preparation. Japan J Pharmacol. 1991;57:397–403
  5. Miller RD. Anesthesia. fourth ed.. Churchill Livingstone Inc.; 1994;p. 742–4
  6. Carp H, Jayaram A, Morrow D. Intrathecal cholinergic agonists lessen bupivacaine spinal block-induced hypotension in rats. Anesth Analg. 1994;79:112–116
  7. Zeng W, Dohi S, Shimonaka H, Asano T. Spinal antinociceptive action of Na+–K+ pump inhibitor ouabain and its interaction with morphine and lidocaine in rats. Anesthesiology. 1999;90:500–508
  8. Langerman L, Grant GJ, Zakkowaki M, Golomb E, Ramanathan S, Turndorf H. Prolongation of epidural anesthesia using a lipid drug carrier with procaine, lidocaine, and tetracaine. Anesth Analg. 1992;75:900–905
  9. Naguib M, Magboul MA. Adverse effects of neuromuscular blockers and their antagonists. Drug Safety. 1998;18:99–116
  10. Inman SR, Stowe NT, Albanese J, Meehan M, Ryckman J, Zanettin GG, et al. Contrasting effects of vecuronium and succinylcholine on the renal microcirculation in rodents. Anesth Analg. 1994;78:682–686
  11. Abelson KS, Hoglund AU. Intravenously administered lidocaine in therapeutic doses increases the intraspinal release of acetylcholine in rats. Neurosci Lett. 2002;317:93–96
  12. Szenohradszky J, Trevor AJ, Bickler P, Caldwell JE, Sharma ML, Rampil IJ, et al. Central nerveous system effects of intrathecal muscle relaxants in rats. Anesth Analg. 1993;76:11304–11309
  13. Mesry S, Baradaran J. Accidental intrathecal injection of gallamine triethiodide. Anesthesia. 1974;29:301–304
  14. Lauretti GR, de Oliveira R, Reis MP, et al. Study of three different doses of epidural neostigmine coadministered with lidocaine for postoperative analgesia. Anesthesiology. 1999;90:1534–1538

PII: S1366-0071(05)00004-5

doi: 10.1016/j.acpain.2005.01.003

Acute Pain
Volume 7, Issue 1 , Pages 37-40 , May 2005

Article Tools

* Image Usage & Resolution