Acute Pain
Volume 7, Issue 1 , Pages 5-11 , May 2005

Postoperative pain and gastro-intestinal recovery after colonic resection with epidural analgesia and multimodal rehabilitation

  • M.U. Werner

      Affiliations

    • Acute Pain Service, Department of Anaesthesiology, Hvidovre University Hospital, Copenhagen, Denmark
    • ,
  • L. Gaarn-Larsen

      Affiliations

    • Acute Pain Service, Department of Anaesthesiology, Hvidovre University Hospital, Copenhagen, Denmark
    • ,
  • L. Basse

      Affiliations

    • Department of Surgical Gastroenterology, Hvidovre University Hospital, Copenhagen, Denmark
    • ,
  • D.H. Jakobsen

      Affiliations

    • Department of Surgical Gastroenterology, Hvidovre University Hospital, Copenhagen, Denmark
    • ,
  • C. Lund

      Affiliations

    • Acute Pain Service, Department of Anaesthesiology, Hvidovre University Hospital, Copenhagen, Denmark
    • ,
  • P. Billesbølle

      Affiliations

    • Department of Surgical Gastroenterology, Hvidovre University Hospital, Copenhagen, Denmark
    • ,
  • H. Kehlet

      Affiliations

    • Department of Surgical Gastroenterology, Hvidovre University Hospital, Copenhagen, Denmark
    • Section for Surgical Pathophysiology 4074, The Juliane Marie Centre, Rigshospitalet, Blegdamsvej 9, DK-2100 Copenhagen, Denmark
    • Corresponding Author InformationCorresponding author. Tel.: +45 3545 4074; fax: +45 3545 6543.

Received 18 May 2004 ,Revised 8 December 2004 ,Accepted 17 January 2005.

References 

  1. Holte K, Kehlet H. Postoperative ileus: a preventable event. Br J Surg. 2000;87:1480–1493
  2. Jørgensen H, Wetterslev J, Møiniche S, Dahl JB. Epidural local anaesthetics versus opioid-based analgesic regimens on postoperative gastrointestinal paralysis, PONV and pain after abdominal surgery (Cochrane Review). Cochrane Database Syst Rev. 2000;4:CD001893
  3. Norris EJ, Beattie C, Perler BA, Martinez EA, Meinert CL, Anderson GF, et al. Double-masked randomized trial comparing alternate combinations of intraoperative anaesthesia and postoperative analgesia in abdominal aortic surgery. Anesthesiology. 2001;95:1054–1067
  4. Kehlet H, Holte K. Effect of postoperative analgesia on surgical outcome. Br J Anaesth. 2001;87:62–72
  5. Kehlet H. Multimodal approach to control postoperative pathophysiology and rehabilitation. Br J Anaesth. 1997;78:606–617
  6. Bardram L, Funch-Jensen P, Kehlet H. Rapid rehabilitation in elderly patients after laparoscopic colonic resection. Br J Surg. 2000;87:1540–1545
  7. Basse L, Jakobsen DH, Billesbølle P, Werner MU, Kehlet H. A clinical pathway to accelerate recovery after colonic resection. Ann Surg. 2000;232:51–57
  8. Senagore AJ, Whalley D, Delaney CP, Mekhail N, Duepree HJ, Fazio VW. Epidural anesthesia–analgesia shortens length of stay after laparoscopic segmental colectomy for benign pathology. Surgery. 2001;129:672–676
  9. Altman DG. Practical statistics for medical research. 1st ed.. London: Chapman & Hall; 1991;
  10. Egbert LD, Battit GE, Welch CE, Bartlett MK. Reduction of postoperative pain by encouragement and instructions of patients. N Engl J Med. 1964;270:825–827
  11. Basse L, Madsen L, Kehlet H. Normal gastrointestinal transit after colonic resection using epidural analgesia, enforced oral nutrition and laxative. Br J Surg. 2001;88:1498–1500
  12. Basse L, Raskov HH, Jakobsen DH, Sonne E, Billesbølle P, Hendel HW, et al. Accelerated postoperative recovery programme after colonic resection improves physical performance, pulmonary function and body composition. Br J Surg. 2002;89:446–453
  13. Carli F, Mayo N, Klubien K, Schricker T, Trudel J, Belliveau P. Epidural analgesia enhances functional exercise capacity and health-related quality of life after colonic surgery: results of a randomized trial. Anesthesiology. 2002;97:540–549
  14. Rigamonti G, Zanella E, Lampugnani R, Marrano D, Campione O, Bruni G, et al. Dose-response study with indoprofen i.v. as an analgesic in postoperative pain. Br J Anaesth. 1983;55:513–519
  15. Collins SL, Moore RA, McQuay HJ. The visual analogue pain intensity scale: what is moderate pain in millimetres?. Pain. 1997;72:95–97

☆ Meetings at which the work has been presented: The study has in part been published as an abstract at the annual meeting of American Society of Anaesthesiologists, New Orleans, 13–17 October 2001.

PII: S1366-0071(05)00002-1

doi: 10.1016/j.acpain.2005.01.001

Acute Pain
Volume 7, Issue 1 , Pages 5-11 , May 2005

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